Carlson Receives NIH Grant to Study Relationship Between Sedentary Time and Cardiovascular Disease
Jordan A. Carlson, PhD, Pediatrics, Center for Children’s Healthy Lifestyles and Nutrition at Children’s Mercy, was recently awarded a five-year, $5,960,344 R01 grant from the National Institutes of Health.
Dr. Carlson’s “Characterization of Sedentary Patterns and Cardiovascular Disease Risk Markers in Hispanics/Latinos” study will work to identify what new information is learned about sedentary bout patterns in free-living population cohorts when they are measured more accurately by the activPAL. The observational cohort study will investigate how various sedentary bout patterns are cross-sectionally and prospectively associated with cardiovascular disease risk markers of adiposity, insulin resistance, and blood glucose in 2,600 Hispanics/Latinos from four regions across the United States.
“We need to move closer to being able to recommend specific limits for sedentary time – How often should sitting bouts be broken up? How long should a break from sitting last? Supporting reductions in prolonged sitting time will complement our existing efforts to increase population physical activity, as both engaging in sufficient physical activity and limiting sedentary time are important for health,” says Dr. Carlson.
Vincent Staggs, PhD, is a co-investigator on the project. Dr. Staggs is a biostatistician and health services researcher in the Biostatistics and Epidemiology Core, which is part of the Division of Health Services and Outcomes Research at Children’s Mercy.
The project has eight subawards.
Children’s Mercy Kansas City is an independent, non-profit, 390-bed pediatric health system, providing over half a million patient encounters each year for children from across the country. Children’s Mercy is ranked by U.S. News & World Report in all ten specialties. We have received Magnet® recognition five times for excellence in nursing services. In affiliation with the University of Missouri-Kansas City, our faculty of nearly 800 pediatric specialists and researchers is actively involved in clinical care, pediatric research and educating the next generation of pediatricians and pediatric subspecialists. The Children’s Mercy Research Institute (CMRI) integrates research and clinical care with nationally recognized expertise in genomic medicine, precision therapeutics, population health, health care innovation and emerging infections. In 2021 the CMRI moved into a nine-story, 375,000-square-foot space emphasizing a translational approach to research in which clinicians and researchers work together to accelerate the pace of discovery that enhances care.